Postmenopausal estrogen and cardiovascular disease. Stampfer MJ, Colditz GA, Willett WC, et al. A change in scientific approach: from alternation to randomised allocation in clinical trials in the 1940s. Streptomycin treatment of pulmonary tuberculosis. MRC Streptomycin in Tuberculosis Trials Committee. Legumes, lemons and streptomycin: a short history of the clinical trial. Evolution of clinical research: a history before and beyond James Lind. On the “probable error” of a coefficient of correlation deduced from a small sample. The manorial response of different potato varieties. ![]() New York: Dover 1868.įisher RA, Mackenzie WA. Strengths and limitations of clinical trials.Clinical trials are essential in establishing the efficacy of pharmacologic and other interventions, but it may be difficult to make decisions on individual patients since the trials include large numbers of participants. As Hippocrates stated in the Aphorisms, Life is short, and art long, opportunity fleeting, experience misleading, and judgment difficult. Making clinical decisions on individual patients after consideration of all strengths and limitations of clinical trials is difficult. For these reasons, this chapter is somewhat eclectic in including important items especially those pertaining to current developments. ![]() Describing the strengths and limitations of clinical trials in a chapter of this book is difficult because of the complexity of the issues, the large number of relevant publications and the accelerating rate of new developments in the field.
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |